Perferidone- A review on analytical methods
DOI:
https://doi.org/10.61096/ijpar.v11.iss2.2022.91-98Keywords:
Pirfenidone, Analytical methods, HPLC, Broad-spectrumAbstract
Pirfenidone is an agent used for the treatment of idiopathic pulmonary fibrosis (IPF). Itis a broad-spectrum antifibrotic medicine was approved in 2014 by USFDA.This review focuses on recent advances in analytical methods for determination of Pirferidone alone or in combination with other medications in pharmaceutical preparations and biological fluids. The analytical techniques UV spectroscopy, high performance liquid chromatography (HPLC), ultra performance liquid chromatography (UPLC), high performance thin layer chromatography (HPTLC), and liquid chromatography linked to tandem mass spectrometry will be thoroughly examined in this study (LC-MS).