Review on pelletization techniques

Authors

  • Prashanthi.P Department of Pharmaceutics, Sri Venkateshwara College of Pharmacy, Affiliated to Osmania University, Madhapur, Hyderabad, India
  • Pavani.A Department of Pharmaceutics, Sri Venkateshwara College of Pharmacy, Affiliated to Osmania University, Madhapur, Hyderabad, India
  • Bhagavan Raju. M Department of Pharmaceutics, Sri Venkateshwara College of Pharmacy, Affiliated to Osmania University, Madhapur, Hyderabad, India

DOI:

https://doi.org/10.61096/ijpar.v8.iss4.2019.523-528

Keywords:

Mutliparticulates, Pellets, Pelletization, Techniques, fluid bed processor, top spray, bottom spray, tangential spray

Abstract

Pellets are multiparticulate dosage form consisting of a multiplicity of small discrete units each exhibit some desired characteristics. Pellets are small free flowing, Spherical or semi spherical units with size and diameter ranging from 0.5-1.5mm. The present review deals with the outline of the pellets, pellets growth mechanism and various types of pelletization techniques like extrusion/spheronization, layering, Cryopelletization, freeze pelletization, spray congealing, spray drying. Among various techniques now-a-days fluid bed processor is most widely used in the pharmaceutical industry due to its uniform coating and highly efficiency. Fluid bed processor involves different spray process i.e top spray, bottom spray and tangential spray. Fluid bed processor has wide range of applications such as drying, particle coating and pelletizing.

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Published

2022-09-26

How to Cite

Prashanthi.P, Pavani.A, & Bhagavan Raju. M. (2022). Review on pelletization techniques. IJPAR JOURNAL, 8(4), 523–528. https://doi.org/10.61096/ijpar.v8.iss4.2019.523-528