Development And Validation Of A Hplc Method For The Determination Of Antidiabetics (Canagliflozin And Metformin) In Api And Pharmaceutical Dosage
DOI:
https://doi.org/10.61096/ijpar.v11.iss2.2022.203-208Keywords:
RP-HPLC, Canagliflozin, Metformin, method development, validation parametersAbstract
A sensitive & selective stability indicting RP-HPLC method has been developed & validated for the analysis of Canagliflozin & Metformin API. Based on peak purity results, obtained from the analysis of samples using described method, it can be concluded that the absence of co-eluting peak along with the main peak of Canagliflozin & Metformin indicated that the developed method is specific for the estimation of Canagliflozin & Metformin. Further the proposed RP-HPLC method has excellent sensitivity, precision and reproducibility.