Optimization of natural and synthetic suspending agents present in diclofenac suspension

Authors

  • S.Valarmathi Department of Pharmaceutics, AnnaiVeilankanni’s college of Pharmacy.Chennai-15 India
  • M. SenthilKumar Department of Pharmaceutics, AnnaiVeilankanni’s college of Pharmacy.Chennai-15 India
  • E.Padmavathy Department of Pharmaceutics, AnnaiVeilankanni’s college of Pharmacy.Chennai-15 India
  • V.Haritha Department of Pharmaceutics, AnnaiVeilankanni’s college of Pharmacy.Chennai-15 India
  • P.Manjula Department of Pharmaceutics, AnnaiVeilankanni’s college of Pharmacy.Chennai-15 India
  • R.Nivedha Department of Pharmaceutics, AnnaiVeilankanni’s college of Pharmacy.Chennai-15 India
  • S.Tharani Department of Pharmaceutics, AnnaiVeilankanni’s college of Pharmacy.Chennai-15 India

DOI:

https://doi.org/10.61096/ijpar.v2017.iss6.2.419-422

Abstract

Suspensions are coarse dispersions defined as a biphasic liquid dosage form of medicaments in which insoluble solid particles are suspended uniformly in a liquid. The size of the insoluble solid particles in liquid phase may exceed 0.1µm.Dispersed phase is also known as internal phase and continuous phase is also known as external phase. Present research work focuses on effect of suspending agents in diclofenac suspension. Both natural and synthetic suspending agents are used. The natural suspending agent i s gelatin and synthetic suspending agent is carbopol. Different concentrations of gelatin (2%, 3%, and 4%) and carbopol ((2%, 3%, and 4%) was prepared. Six formulations with formulation code of F1, F2, F3, F4, F5, and F6 was formulated. The prepared suspen sions are evaluated for viscosity,pH, sedimentation volume, degree of flocculation, particle size etc.

 

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Published

2022-09-29

How to Cite

S.Valarmathi, M. SenthilKumar, E.Padmavathy, V.Haritha, P.Manjula, R.Nivedha, & S.Tharani. (2022). Optimization of natural and synthetic suspending agents present in diclofenac suspension. IJPAR JOURNAL, 2017(6), 419–422. https://doi.org/10.61096/ijpar.v2017.iss6.2.419-422