A simple validated RP-HPLC method for quantification of sumatriptan succinate in bulk and pharmaceutical dosage form

Authors

  • Jampala Balaji
  • K.Aruna
  • N.V.S.Naidu

DOI:

https://doi.org/10.61096/ijpar.v4.iss1.2015.83-87

Keywords:

Sumatriptan succinate, Reverse phase HPLC, Hypersil BDS C18, Isocratic elution

Abstract

A simple reverse phase high performance liquid chromatography method developed for quantification of sumatriptan
succinate in bulk and pharmaceutical dosage form. This method achieved by using isocratic elution with mixed
phosphate buffer (pH: 6.8) and acetonitrile mobile phase at 70:30 ratio, Hypersil BDS C18 (150 X 4.6mm, 5µm) column
at temperature 30ºC, flow rate 1.0mL/min and 228nm UV with PDA detector. This method validated as per ICH
guidelines. This method was simple, specific, precise, linear, accurate, robust and ruggedness for analysis of sumatriptan
succinate.

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Published

2015-01-31

How to Cite

Jampala Balaji, K.Aruna, & N.V.S.Naidu. (2015). A simple validated RP-HPLC method for quantification of sumatriptan succinate in bulk and pharmaceutical dosage form. IJPAR JOURNAL, 4(1), 83–87. https://doi.org/10.61096/ijpar.v4.iss1.2015.83-87

Issue

Vol. 4 No. 1 (2015): 2015 Volume - 4 Issue - 1

Section

Articles