Fluoroquinolone as anticancer agents: An overview

Authors

  • G. Tamilarasi Assistant professor, Department of Pharmaceutical chemistry, College of pharmacy, Madurai medical college, Madurai, Tamilnadu, India.
  • G. Umarani Associate professor, Department of Pharmaceutical chemistry, College of pharmacy, Madurai medical college, Madurai, Tamilnadu, India.
  • P. Keerthana II year M.Pharm, Associate professor, Department of Pharmaceutical chemistry, College of pharmacy, Madurai medical college, Madurai, Tamilnadu, India.
  • I. Selvamatha II year M.Pharm, Department of Pharmaceutical chemistry, College of pharmacy, Madurai medical college, Madurai, Tamilnadu, India.
  • R. Thirupathi II year M.Pharm, Department of Pharmaceutical chemistry, College of pharmacy, Madurai medical college, Madurai, Tamilnadu, India.

Keywords:

Quinolone, fluoroquinolone, DNA gyrase, topoisomerase 4, antibiotic, anticancer

Abstract

Quinolones and fluoroquinolones are the most kind of antibacterial agents. Fluoroquinolones one of the type of antibacterial agents extensively used from the past few years and will be continued to be used in the next decade. Fluoroquinolones exerting the antibacterial activity through binding to type 2 bacterial topoisomerase enzymes, DNA gyrase and topoisomerase 4 are mainstays in chemotherapy. Antibacterial agents are chemical agents which is used to treat the infection by bacterial, viral, fungal and microorganism infection. This review aims to highlight the classification, structural activity relationship and recent update for fluoroquinolone as anticancer and antibacterial activity.

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Published

2024-11-04

How to Cite

G. Tamilarasi, G. Umarani, P. Keerthana, I. Selvamatha, & R. Thirupathi. (2024). Fluoroquinolone as anticancer agents: An overview. IJPAR JOURNAL, 13(4), 618–622. Retrieved from https://ijpar.com/ijpar/article/view/821

Issue

Vol. 13 No. 4 (2024): 2024 Volume - 13 Issue - 4

Section

Articles