Fluoroquinolone as anticancer agents: An overview
Keywords:
Quinolone, fluoroquinolone, DNA gyrase, topoisomerase 4, antibiotic, anticancerAbstract
Quinolones and fluoroquinolones are the most kind of antibacterial agents. Fluoroquinolones one of the type of antibacterial agents extensively used from the past few years and will be continued to be used in the next decade. Fluoroquinolones exerting the antibacterial activity through binding to type 2 bacterial topoisomerase enzymes, DNA gyrase and topoisomerase 4 are mainstays in chemotherapy. Antibacterial agents are chemical agents which is used to treat the infection by bacterial, viral, fungal and microorganism infection. This review aims to highlight the classification, structural activity relationship and recent update for fluoroquinolone as anticancer and antibacterial activity.