Formulation and Evaluation of Praziquantel Tablets (600 Mg)

Abstract

     The aim of this study is to develop immediate release praziquantel tablets with the use of sodium Lauryl sulphate as it's main function as a solubility enhancer and croscarmellose sodium as a super disintegrants. Formulation is carried out by wet granulation procedure and followed with post evaluation studies which include, Weight variation test, Hardness test, friability test, disintegration test and dissolution test.The relative dissolution study was performed in diverse media, with and without the utilization of the surfactant. The summary results show that the test product (Praziquantel tablets 600mg) is comparable to reference product(Biltricide tablets 600mg), Since the F1 and F2 values are found to be within limits. All the physical and chemical parameters are found competent and lined -up to the quality target product profile.