Buddchiari syndrome associated miscarriage - A case report

Authors

  • Hashif PharmD Intern, Aster CMI Hospital, sahakarnagar, Bengaluru-560082, India.
  • Poornima Pankaj PharmD Intern, Aster CMI Hospital, sahakarnagar, Bengaluru-560082, India.
  • Praveen Kumar Clinical Pharmacist, Aster CMI Hospital, sahakarnagar, Bengaluru-560082, India.

DOI:

https://doi.org/10.61096/ijpar.v10.iss3.2021.341-342

Keywords:

buddchiari syndrome, pregnancy, miscarriage, spontaneous abortion, antepartum haemorrhage

Abstract

Budd–Chiari syndrome (BCS) is described as blockage of the outflow of hepatic veins. This obstruction could be detected anywhere between the small hepatic veins to the suprahepatic inferior vena cava (IVC). BCS can be classified as two groups: primary and secondary. BCS is observed as primary when blockage of the outflow of hepatic veins is the outcome of an endoluminal venous lesion which could be either thrombus or web and its observed as secondary when blockage of hepatic veins originates from a lesion outside the venous system which could be a tumor or an abscess or cysts.

A pregnant patient of 26 years was admitted in the OBG department of Aster CMI hospital, Hebbal, Bengaluru with complaints of increased bleeding and abdominal pain who was diagnosed with Buddchiari syndrome 2 years back. This is her 2nd pregnancy and she had a history of spontaneous miscarriage at 5 weeks period of gestation( POG). On the 3rd day of admission, abortus fetus was delivered followed by placental delivery blood transfusion was also done.

With a prevalence of 1 in 1 lakhs  to 5 lakhs, primary BCS is a rare disorder, majorly detected by imaging, whereas options of therapy consists of a step-wise approach with medication (anticoagulation), minimally invasive procedures like thrombolysis, percutaneous angioplasty, transjugular intrahepatic portosystemic shunting (TIPS), and surgical portosystemic shunting and orthotopic liver transplantation (LTX). BCS is rare and clinically challenging disease.

 

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Published

2022-08-26

How to Cite

Hashif, Poornima Pankaj, & Praveen Kumar. (2022). Buddchiari syndrome associated miscarriage - A case report. IJPAR JOURNAL, 10(3), 341–342. https://doi.org/10.61096/ijpar.v10.iss3.2021.341-342