Orally disintegrating tablets: A review

Authors

  • S. Sripriya Department of Pharmaceutical Science, K.K. College of Pharmacy, Chennai, Tamil Nadu, India
  • Senthil Kumaran Department of Pharmaceutical Science, K.K. College of Pharmacy, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.61096/ijpar.v10.iss4.2021.372-381

Keywords:

Improved bioavailability, orally disintegrating tablets, Superdisintegrants.

Abstract

Orally Disintegrating Tablet (ODT) is such type of an innovative and unique drug delivery system which is gaining more attention and attraction in the research field of rapidly dissolving technology. ODTs are solid dosage forms containing active ingredients which dissolve or disintegrate quickly within a second, when placed on tongue. ODT technologies address the need of geriatric, pediatric and psychiatric patients who may feel difficulty in swallowing, thus ODTs are preferred alternative to conventional tablet and capsules due to better patient compliance. In the design of drug delivery system, comforts of drug administration and patient conformity have considerable prominence. They are several methods employed for preparing ODTs conventionally are spray drying, freeze drying, direct compression, melding, and sublimation while new technologies have been developed for the formulation of orodispersible tablets. This article emphasis the various aspects of ODT formulation and to review the development of ODTs, new ODT technologies and evaluation methodologies, mechanism of super disintegration, challenges faced during formulation and its limitations.

 

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Published

2022-08-29

How to Cite

S. Sripriya, & Senthil Kumaran. (2022). Orally disintegrating tablets: A review. IJPAR JOURNAL, 10(4), 372–381. https://doi.org/10.61096/ijpar.v10.iss4.2021.372-381