Content Variation Studies of Marketed Monoherbal Formulations Containing Bacopa monnieri By HPLC Technique

Abstract

The standardization of herbal formulations has become very essential as there is increase in the demand and frequent usage of the herbal formulations by the people. Monoherbal formulations containing Bacopa monnieri extract were collected from the commercial market and analysed for their phytoconstituents viz: Bacopaside-I,  Bacoside A3, Bacopaside-II, Jujubogenin isomer of Bacopasaponin C and Bacopasaponin C contents by High Performance Liquid Chromatographic Technique (HPLC). The Capsule and Powder forms of different brands of marketed herbal formulations of Bacopa monnieri were selected and analysed by HPLC Technique. The total peak area of standards and the corresponding peak area of samples were compared and the amount present in them was calculated. The results reveal that there are lots of variations between marketed Bacopa products and the content of phytochemicals are not uniform. The present study indicates the necessity of development of analytical procedures for all herbal formulations available in the market to ensure the quality and efficacy of the products.