Design, formulation and evaluation of a polyherbal gel for its wound healing activity

Authors

  • Raju Darla Assistant professor department of pharmacy,hits college of pharmacy, bogaram keesara Rangareddy district.501301,telangana state,india.
  • Srisailam keshetti Principal, University College of pharmaceutical sciences,satavahana University, karimnagar.505305 Telangana state, India.

DOI:

https://doi.org/10.61096/ijpar.v10.iss2.2021.226-232

Keywords:

Tridax procumbens, Cassia occidentalis, polyherbal formulation,excision wound method

Abstract

The present study was aimed at designing, formulating and evaluating a polyherbal gel comprising of ethanolic extract of the leaves Tridax procumbens and petroleum ether extract of the leaves Cassia occidentalis have a great medicinal value for its wound and burn healing properties. The animals were divided into groups and were treated with polyherbal formulation, standard group and one served as control group.5% w/w betadine powder was used as reference standard. The period of epithelization in the excision wound mode was found to be 12 days.  Different  parameters  like  pH,  viscosity,  spreadability  and  stability  were  evaluated.  The  formulation showed good spreadability, good consistency, homogeneity, there was no change in the appearance, pH, and no phase separation noticed at the end of the stability studies. There was no evidence of skin irritation. This study has revealed that the poly herbal gel has shown the wound healing effect due to the synergistic activity of the phytoconstituents present in the extracts and may be used a potential herbal formulation for wound healing

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Published

2022-08-26

How to Cite

Raju Darla, & Srisailam keshetti. (2022). Design, formulation and evaluation of a polyherbal gel for its wound healing activity . IJPAR JOURNAL, 10(2), 226–232. https://doi.org/10.61096/ijpar.v10.iss2.2021.226-232