The Therapeutic Prospects of Abutilon indicum (L.) Sweet: An Integrative Review of Pharmacology and Physicochemical Properties

Abstract

Abutilon indicum (L.) Sweet, also known as Indian Mallow, is a key component of traditional medicine systems such as Ayurveda, Siddha and Unani. This integrative review combines current pharmacological evidence and physicochemical data to assess therapeutic potential and set quality control standards. Preclinical research reveals a diverse pharmacological profile, including significant hepatoprotective, anti-inflammatory, analgesic, and antidiabetic properties. notably, the plant has specialized properties such as wound healing through collagen synthesis, anti-asthmatic effects through mast cell stabilization, and strong larvicidal action against major mosquito vectors. flavonoids, alkaloids, and beta-sitosterol are among the bioactive secondary metabolites that contribute to these activities. furthermore, this review compiles key physicochemical parameters such as extractive values and ash content from various plant parts to aid in the standardization of herbal formulations. While A. indicum remains a promising candidate for evidence-based phytopharmaceuticals, the transition from bench to bedside necessitates extensive clinical trials to ensure human safety and efficacy.