Formulation and Evaluation of Euphorbia Hirat Based on Herbal Ointment to Treat Wart

Abstract

Warts are benign skin growths caused by infection with the Human papillomavirus (HPV), which leads to excessive keratin formation in the epidermis. The present study aimed to formulate and evaluate an herbal ointment containing Euphorbia hirta leaf extract for its keratolytic activity. The ointment was prepared using the fusion method and evaluated for its physicochemical properties, hemolytic assay, and keratin degradation ability. The formulation showed acceptable physical characteristics, good spread ability, and was found to be non-irritant and suitable for topical application. The results suggest that the Euphorbia hirta herbal ointment may be beneficial in the management of hyperkeratotic skin conditions such as warts.