Antidiabetic properties of Jamun (syzygium cumini)

Abstract

Syzygium cumin (Family-Myrtaceae) is a medicinal plant commonly recommended as adjuvant therapy for type 2 diabetes. This plant has been thoroughly researched over the last 125 years. This plant has traditionally been used for its rich nutrition and medicinal value. The current review focuses on a recent research study that included Jamun's unique pharmacy studies. Jamun plant is reported to be rich in phytoconstituents such as ellagic acid, glucoside, anthocyanins, kaempferol, isoquercetin, myrecetin and so on. The seeds most commonly used for their medicinal value are said to contain alkaloid-jambosine and glycoside-jambolin or antimellin to prevent the conversion of starch into sugar. Different plant parts are said to contain different nutrients Jamun has long been used to treat diabetes. Apart from this it has also shown its beneficial properties as anti-allergic, antibacterial, anti-cancer,anti-diarrheal, anti-fertility, anti-fungal, anti-hyperlipidemic, anti-hypertensive, anti inflammatory, antilieshmanial, antinociceptive, antioxidant, antiviral, ascaricidal, cardioprotective, chemoprotective, diuretic, gastroprotective, hepatoprotective, hypothermic, neuropsycho pharmacological and radioprotective agent. Jamun may activate PPARγ and PPARα genes that suppress NF κB, COX, NOS, TNF - α and other inflammatory cytokines are followed by Nrf2 regulation.