A Review on analytical techniques for the estimation of Posaconazole in pharmaceutical dosage form

Authors

  • D. Praneetha
  • Dr. T. Rama Rao Pharmaceutical Analysis, CMR College of Pharmacy, JNTUH, Hyderabad-501401, Telangana, India

Keywords:

Posaconazole, HPLC, Spectroscopy, LC-MS, Pharmaceutical analysis.

Abstract

Pharmaceutical drugs play a vital function in human existence by aiding in the treatment of various disorders. As a consequence, developing analytical methods has become the primary activity of analysis. People have been searching for safe and effective ways to cure viral infections since ancient times. Due to the emergence of new fungal infections, the discovery of medications for their treatment is becoming equally important in the contemporary context. These medications should be validated before they are released to the market. High-performance liquid chromatography (HPLC) in conjunction with ultraviolet (UV), photodiode array detectors (PDA), mass spectrophotometer (MS) detectors, and other technologies is one of the quickest, safest, and most precise methods for determining and separating pharmaceutical drugs, impurities, and biological samples. When compared to older liquid chromatography techniques, HPLC is more flexible and takes less time to quantify pharmaceuticals. Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients. The current research demonstrated that the HPLC technique, as well as the spectroscopic approach, has been the most commonly examined for analysis. The investigatory review may give thorough facts to researchers functioning in the Posaconazole analytical study.

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Published

2022-04-13