Retrospective study on antibiotic use in different clinical departments of hospital in Nalut, Libya

Abstract

A retrospective Study on Antibiotic Use in Different Clinical Departments of Hospital in Nalut, Libya during a period of five  months (1/1/2013to 30/5/2013). Data  were collected retrospectively from inpatients medical files (600 patient's medical file), prescriptions for outpatients (400 prescriptions studied) and the total number of prescription was 1000. The data then was evaluated by Microsoft Excel software for analysis and descriptive statistics. The World Health Organization (WHO) indicators (utilization in defined daily doses (DDD); DDD/1000 inh/day) were used and the ATC/ DDD method was implemented. The three most frequently used antibiotics for inpatients were cefotaxime, ceftriaxone and metronidazole with 25.57%, 16.54% and 15.34% of the total prescribed antibiotics respectively, and for outpatients they were amoxiclav (26.23%), amoxicillin and azithromycin (12.41%) and ciprofloxacin (11.48%). After  calculating the  consumption of  antibiotics in  DDD,  the  highest  consumed  antibiotic  in  DDDs  (g)  was clarithromycin 10.67 g and 0.119 g in terms of DDD/1000inh/day, while consumption of amoxiclav was the lowest consumption 0.011 g and 0.00012 DDD/1000 in h/day. About 98% of patients given antibiotics without culture sensitivity tests (c/s). Only 2% of the patients undergone the test during the treatment. In conclusion, this study we identified that the DDD for antibiotic consumption data for five months and the clarithromycin was the most consumption over those months and we find out the most prescribed antibiotics and the most of the wards use it. In addition to the demographic data, this also helps physicians to have a more precise idea about prescriptive patterns prevalent in the Libyan community.