Colontargeting drug delivery system

Abstract

The colonic drug delivery refers to the drug that should released in the colonic environment rather than in the upper gastrointestinal tract. To achieve the site-specificity of the local treatment of the colon such as amoebiasis, colorectal cancer, and inflammatory bowel disease the target-specific drug delivery reacts as an important role. For the target-specific drug delivery to the colon, the various technique that has be explored include pH-dependent polymer, time- dependent, and bacteria-dependent drug delivery technique. Even the Nanotechnology has been gained a lot interest due to ta specificity and improved of bioavailability and high loading capacity as well. In this review, oral different formulation for colon targeting particular techniquees to enhancement of drug stability in the gastric environment has been included.