A review on comparison of specific serum immunoglobulin g and complement c3 levels in gestational diabetics and normal healthy pregnant women and its complications during pregnancy.

Authors

  • Mathew George Department of Pharmacology, Pushpagiri College of Pharmacy, Thiruvalla-689107, Kerala, India.
  • Lincy Joseph Department of Pharmaceutical Chemistry, Pushpagiri College of Pharmacy, Thiruvalla-689107, Kerala, India.
  • Leena P.N Department of Pharmacognosy, Pushpagiri College of Pharmacy, Thiruvalla -689107, Kerala, India.
  • Jeena Varghese Department of Pharmacognosy, Pushpagiri College of Pharmacy, Thiruvalla -689107, Kerala, India.

Keywords:

Gestational diabetes mellitus, Immunoglobulin G, Complement C3, Immunity, Complications

Abstract

Gestational diabetes mellitus is one of the most common medical complication and a metabolic disorder that occurs during pregnancy. The essential components of humoral immunity are complement and circulating immunoglobulin. Immunoglobulin (Ig),is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to identify and neutralize pathogens such as bacteria and viruses. The complement system, a complex protein network initially identified as part of the innate immune system, is as an essential regulator of cell and tissue homeostasis.. Maternal antibodies Ig G are transported across the placenta which protects the newborn.  As there are o nly few studies in Indian literature regarding the comparison of  specific serum immunoglobulin g and complement c3 levels in gestational diabetics and normal healthy pregnant women .This review is design to compare the levels  of serum immunoglobulin G  and  complement C3  in  Gestational diabetics and  normal  healthy pregnant  woman and  its complications during pregnancy.

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Published

2022-09-14