New analytical method development for the estimation of minoxidil by rp hplc method

Authors

  • G. Keerthi Omega College of Pharmacy, Edulabad, Ghatkesar, Affiliated to Osmania University, Hyderabad, Telangana.
  • H. Parameshwar Omega College of Pharmacy, Edulabad, Ghatkesar, Affiliated to Osmania University, Hyderabad, Telangana.
  • A.V. Jithan Omega College of Pharmacy, Edulabad, Ghatkesar, Affiliated to Osmania University, Hyderabad, Telangana.
  • K. Sindhoora Omega College of Pharmacy, Edulabad, Ghatkesar, Affiliated to Osmania University, Hyderabad, Telangana.

DOI:

https://doi.org/10.61096/ijpar.v11.iss2.2022.216-222

Keywords:

RP-HPLC, Minoxidil, Validation parameters, Estimations

Abstract

In the present work RP-HPLC method for estimation Minoxidil has been developed. The proposed methods are precise, accurate and do not suffer from any interference due to common excipient. The validation parameters according to I.C.H Q2B guidelines were studied. The accuracy of the methods was proved by performing recovery studies in newly developed formulations. Values greater than 98% indicate that the proposed method is accurate for the analysis of drug. A sensitive & selective stability indicting RP-HPLC method has been developed & validated for the analysis of Minoxidil API.  The result shows the developed method is yet another suitable method for assay and stability studies which can help in the analysis of Minoxidil different formulations.

Further the proposed RP-HPLC method has excellent sensitivity, precision and reproducibility.

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Published

2022-06-20

How to Cite

G. Keerthi, H. Parameshwar, A.V. Jithan, & K. Sindhoora. (2022). New analytical method development for the estimation of minoxidil by rp hplc method. IJPAR JOURNAL, 11(2), 216–222. https://doi.org/10.61096/ijpar.v11.iss2.2022.216-222

Issue

Vol. 11 No. 2 (2022): 2022 Volume - 11 Issue - 2

Section

Articles