Rationale and inconceivable liver function catechism

Authors

  • S. Gopinath Senior Team Leader, Strides Pharma Science Limited, Bilekahalli, Bengaluru – 560076, Karnataka.
  • K. Kathiresan Assistant Professor, Department of Pharmacy, Annamalai University - 608002, Chidambaram, Tamil Nadu, India.

DOI:

https://doi.org/10.61096/ijpar.v6.iss4.2017.783-789

Abstract

Inconceivable liver function catechism are defined as increased levels of static biochemical tests, which include liver tests measured in serum -  Aspartate Transaminase (AST), Alanine Transaminase (ALT), Alkaline phosphatase (ALP), bilirubin and measurements of biosynthetic liver function and International Normalized Ratio (INR), albumin. Common complaints include fatigue, malaise, nausea, hematemesis or melena/ haematochezia, pruritus, jaundice, easy  bruising,  anorexia,  weight  loss,  abdominal  swelling  or  right  upper  quadrant  discomfort,  confusion,  and decreased libido or erectile dysfunction.  The severity of the complaints is often related to the acuteness and severity of the liver injury. Even patients with advanced liver disease may remain asymptomatic, with normal or only mildly abnormal LFTs. Physical findings in patients with abnormal liver function catechism, Hepatomegaly or an unusually firm liver may be present.  Jaundice, spider angiomata, palmar erythema, Terry nails, ascites, splenomegaly, dilated periumbilical veins, hemorrhoids, asterixis, edema, and testicular atrophy, gynecomastia, or loss of pubic and axillary hair may all be signs of liver disease.

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Published

2017-12-25

How to Cite

S. Gopinath, & K. Kathiresan. (2017). Rationale and inconceivable liver function catechism. IJPAR JOURNAL, 6(4), 783–789. https://doi.org/10.61096/ijpar.v6.iss4.2017.783-789