Rationale and inconceivable liver function catechism
DOI:
https://doi.org/10.61096/ijpar.v6.iss4.2017.783-789Abstract
Inconceivable liver function catechism are defined as increased levels of static biochemical tests, which include liver tests measured in serum - Aspartate Transaminase (AST), Alanine Transaminase (ALT), Alkaline phosphatase (ALP), bilirubin and measurements of biosynthetic liver function and International Normalized Ratio (INR), albumin. Common complaints include fatigue, malaise, nausea, hematemesis or melena/ haematochezia, pruritus, jaundice, easy bruising, anorexia, weight loss, abdominal swelling or right upper quadrant discomfort, confusion, and decreased libido or erectile dysfunction. The severity of the complaints is often related to the acuteness and severity of the liver injury. Even patients with advanced liver disease may remain asymptomatic, with normal or only mildly abnormal LFTs. Physical findings in patients with abnormal liver function catechism, Hepatomegaly or an unusually firm liver may be present. Jaundice, spider angiomata, palmar erythema, Terry nails, ascites, splenomegaly, dilated periumbilical veins, hemorrhoids, asterixis, edema, and testicular atrophy, gynecomastia, or loss of pubic and axillary hair may all be signs of liver disease.