Novel and efficient cytotoxic 2-alkyl, 4-chloro-5,6-dihydro-2h-pyran derivatives of aplysiapyranoids a-d,an anti solod tumer of human cells.

Authors

  • V. Harikrishna Division of Organic Chemistry-I, Discovery Laboratory, Indian Institute of Chemical Technology, Hyderabad-500007, India.
  • Gnaneswar Duggheni Division of Organic Chemistry-I, Discovery Laboratory, Indian Institute of Chemical Technology, Hyderabad-500007, India.

DOI:

https://doi.org/10.61096/ijpar.v5.iss1.2016.179-182

Keywords:

Coupling of Alkynes to Aldehydes, Regioselective and Efficient, Cyclization is promoted by the Ionic Liquid

Abstract

Cytotoxic 2-alkyl, 4- chloro-5, 6- dihydro-2H-pyran derivatives were first synthesized in single step method by using recyclable catalytic chloroaluminate immobilized in ionic liquids the reaction of aldehydes and ketones with homopropargylic alcohols using chloroaluminate ionic liquids generated the dihyropyran derivatives in good yields and with high stereoselectivity.

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Published

2016-02-20

How to Cite

V. Harikrishna, & Gnaneswar Duggheni. (2016). Novel and efficient cytotoxic 2-alkyl, 4-chloro-5,6-dihydro-2h-pyran derivatives of aplysiapyranoids a-d,an anti solod tumer of human cells. IJPAR JOURNAL, 5(1), 179–182. https://doi.org/10.61096/ijpar.v5.iss1.2016.179-182

Issue

Vol. 5 No. 1 (2016): 2016 Volume - 5 Issue - 1

Section

Articles