Gas chromatography-Mass spectrometry-A Review

Abstract

This small critique discusses the analytical technique on gas chromatography mass spectrometry specifically basic principles and  instrumentations. The  applications of  GC-MS to  a  number of  studies for  determining organic compounds from around the world are presented and highlight its universal use and acceptance. GC-MS is an integral and complimentary part of many field studies involving organic compound detection and determination.GC/MS is limited to analytes that are not only volatile and thermally labile but can also withstand the harsh partitioning condition of the gas chromatograph. Extensive fragmentation experienced during electron ionisation(EI), in positive & negative mode. There are many compounds that produce unique patterns that can be used in conjunction with gas chromatographic time data for an univocal identification.Considering that GC evolved as popular technology almost six decades ago & given the standardisation methods using the retention index & kovats index.