A Simple Validated RP-HPLC Method for Quantification of Azilsartan Medoxomil in Bulk and Pharmaceutical Dosage Forms

Authors

  • Jampala Balaji
  • Bandi Ramachandra
  • Niranjan
  • N.V.S.Naidu

DOI:

https://doi.org/10.61096/ijpar.v4.iss3.2015.381-385

Keywords:

Azilsartan Medoxomil, Reverse Phase HPLC, UV-Visible detector, Isocratic elution

Abstract

A simple reverse phase high performance liquid chromatography method developed for quantification of Azilsartan
Medoxomil in bulk and pharmaceutical dosage forms. This method achieved by using isocratic elution with mixed
phosphate buffer (pH: 6.8 ± 0.1) and acetonitrile mobile phase at 80:20 ratio, Zodiac C18 column (100 X 4.6mm, 3µm) at
temperature 30ºC, flow rate 1.0mL/min and 243nm UV-Visible detector. This method validated as per ICH guidelines.
This method was simple, specific, precise, linear, accurate, robust and ruggedness for analysis of Azilsartan Medoxomil.

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Published

2015-09-03

How to Cite

Jampala Balaji, Bandi Ramachandra, Niranjan, & N.V.S.Naidu. (2015). A Simple Validated RP-HPLC Method for Quantification of Azilsartan Medoxomil in Bulk and Pharmaceutical Dosage Forms. IJPAR JOURNAL, 4(3), 381–385. https://doi.org/10.61096/ijpar.v4.iss3.2015.381-385