A Simple Validated RP-HPLC Method for Quantification of Azilsartan Medoxomil in Bulk and Pharmaceutical Dosage Forms
Keywords:Azilsartan Medoxomil, Reverse Phase HPLC, UV-Visible detector, Isocratic elution
A simple reverse phase high performance liquid chromatography method developed for quantification of Azilsartan
Medoxomil in bulk and pharmaceutical dosage forms. This method achieved by using isocratic elution with mixed
phosphate buffer (pH: 6.8 ± 0.1) and acetonitrile mobile phase at 80:20 ratio, Zodiac C18 column (100 X 4.6mm, 3µm) at
temperature 30ºC, flow rate 1.0mL/min and 243nm UV-Visible detector. This method validated as per ICH guidelines.
This method was simple, specific, precise, linear, accurate, robust and ruggedness for analysis of Azilsartan Medoxomil.