Aquasomes: A Novel Carrier for Drug Delivery

Abstract

This method is known worldwide for nanoparticular carriers is referred to as aquasoms.Aquasomes are the type of nanoparticles and made up of three layered self-assembled structures, consisting of a solid phase nanocrystalline core covered  with  oligomeric  film,  biochemically  active  molecules  that  are  typically absorbed  with  or  without modification.Aquasomes are a nano-biopharmaceutical carrier device consisting of a particle center consisting of a nanocrystalline calcium phosphate or a ceramic diamond surrounded by a polyhydroxy oligomeric film.Aquasomes are spherical in forms containing 60-300 nm particles used for drug and antigen distribution. Their characteristics are that they  shield  and  maintain  delicate biological  molecules,  conformation  integrity,  and  surface  visibility,  allowing aquasomes a good carrier mechanism for unique sites for bio-active molecules such as peptides, proteins, hormones, antigens, and genes. Three types of core materials are primarily used for the processing of Aquasomes: tin oxide, nanocrystalline carbon ceramic (diamonds) and brushite (calcium phosphate dihydrate). Brushite is unstable, and it is converted to hydroxyapatite when stored for a long time, and Calcium Phosphate is the core that is naturally present in the body. As a result, hydroxyapatite appears to be the better core for aquasome preparation. It's primarily used in the preparation of implants for drug delivery. Drug delivery via aquasomes is facilitated by precise targeting, molecular sheeling, and a slow, sustained release process.