SPECTROPHOTOMETRIC ESTIMATION OF ROSUVASTATIN CALCIUM IN BULK & PHARMACEUTICAL FORMULATIONS

Authors

  • Chandni Saha Department of Pharmaceutical Analysis, Bharat Institute of technology, JNTU Mangalpally (V), Ibrahimpatnam (M), Ranga Reddy District-501510.
  • G.Sreelatha Department of Pharmaceutical Analysis, Bharat Institute of technology, JNTU Mangalpally (V), Ibrahimpatnam (M), Ranga Reddy District-501510.
  • Md.Nazeeruddin Ahmed Kingdom of Saudi Arabia.

DOI:

https://doi.org/10.61096/ijpar.v2.iss3.2013.84-88

Keywords:

Rosuvastatin calcium, Water, UV spectrophotometer.

Abstract

Rosuvastatin calcium of the class statins is used for primary hyperlipidemias. It is a selective and competitive inhibitor of HMG-CoA reductase. In the present work, simple, sensitive and economic spectrophotometric method has been developed for quantitative determination of Rosuvastatin calcium.   In the present spectrophotometric method  Rosuvastatin calcium was  dissolved in  double  distilled  water.  It  exhibited an absorption maximum at 241 nm and obeyed Beer’s law in the concentration range of 5 -25mg/ml. The results of analysis have been validated and found to be sensitive, precise and accurate for quantitative determination of Rosuvastatin calcium in bulk drug and pharmaceutical formulations.

Downloads

Published

2013-09-15

How to Cite

Chandni Saha, G.Sreelatha, & Md.Nazeeruddin Ahmed. (2013). SPECTROPHOTOMETRIC ESTIMATION OF ROSUVASTATIN CALCIUM IN BULK & PHARMACEUTICAL FORMULATIONS. IJPAR JOURNAL, 2(3), 84–88. https://doi.org/10.61096/ijpar.v2.iss3.2013.84-88

Issue

Vol. 2 No. 3 (2013): 2013 Volume - 2 Issue - 3

Section

Articles