Screening of analgesic and antipyretic properties on ethanolic extract of argemone mexicana linn

Abstract

The aim of this study was to investigate the analgesic and antipyretic properties of ethanolic extract of Argemone mexicana
Linn. Also, the Phytochemical screening was conducted and the extract showed the presence of flavonoids, alkaloids,
terpenoids, tannins, and steroids. Analgesic and antipyretic effects of ethanolic extract of Argemone mexicana linn were
investigated at doses of 50 mg/kg b.w. and 100 mg/kg b.w. using tail immersion and yeast-induced pyrexia tests. Oral
administration of Argemone mexicana ethanolic extract produced significant (P<0.001) raised the pain threshold at different
time of observation (0-150min) in comparison with control. Tested on yeast-induced pyrexia in rats, significantly (P<0.0001)
reversed hyperthermia at different does level. The results of pharmacological studies performed in the present study suggest
that the extract possesses potent analgesic and antipyretic effects.