Analytical method development and validation for the estimation of favipiravir by using rp-uplc method

Abstract

Chromatographic separation was achieved on mobile phase consisting of a mixture of Methanol: Acetonitrile: Water in ratio 50: 30: 20 v/v/v with detection of 229 nm. Linearity was observed in the range 50-150µg/ml for Favipiravir (r² =0.9974) for drug estimated by the proposed methods was in good agreement with the label claim. It was concluded that, this newly developed method for the simultaneous estimation of Favipiravir was found to be simple, precise, accurate and high resolution and shorter retention time makes this method more acceptable and cost effective and it can be effectively applied for routine analysis in research institutions, quality control department in meant in industries, approved testing laboratories studies in near future.