A Review On Complexometric Titrations Used In Assay Of Various Drugs

Abstract

Utilising complex-forming processes, complexometric titrations, also known as chelatometry, are a method for determining metal ions. In this kind of volumetric analysis, the formation of a coloured complex indicates the titration endpoint. The interaction between the metal ion and ligand, which leads to the creation of a complex, is the main idea in various types of titrations. The resultant compound is stable and dissolves in water. The complexometeric titrations use a variety of indicators, including Solochrome black T, Eriochrome black T, Mordant black II, Murexide, and Cathechol violet. This method of titrations can be used to measure the hardness of the water as well as the amounts of calcium, magnesium, zinc, and copper ions in the sample.  Complexometric titrations are frequently used to measure a mixture of many metal ions in solution.