Reviewing the development and validation of analytical methods for different drugs utilizing uv spectroscopy
DOI:
https://doi.org/10.61096/ijpar.v13.iss3.2024.354-363Keywords:
Fenofibrate, ranolazine, pantoprazole, UV-visible spectrophotometerAbstract
UV-visible spectrophotometry refers to absorption spectroscopy. It provides fast and efficient analysis. It is used to quantify nucleic acid and protein content in biological samples and for quality control in drugs and food industries. It is based on the interaction between light and matter. It is used in the wavelength range of 190-900nm. Many drugs are analyzed by UV visible spectrophotometer. Fenofibrate is an oral medication of the fibrate class used to treat abnormal lipid levels. It works by increasing the natural substance that breaks down the fats in the blood. It is less commonly used when compared with statins because it treats a different type of cholesterol abnormality than statins. Ranolazine is an anti-anginal drug. It is used to treat chronic angina (cardiovascular illness). It is used concomitantly with angiotensin receptor β-blockers, and ACE inhibitors. Pantoprazole is an anti-ulcer (proton pump inhibitor). It irreversibly inhibits the gastric H+/K+-ATPase inhibitors. It is metabolized in the liver and excreted through urine.