Biosynthesis And Assessment Of Antibacterial Activity Of Silver Nanoparticles Utilizing Herbal Extract

Authors

  • Ubaidulla Uthumansha Department of Pharmaceutics, Crescent School of Pharmacy, B.S. Abdur Rahman Crescent Institute of Science and Technology, GST Road, Vandalur, Chennai, Tamil Nadu, India
  • Mohammad Samiyullah. S Department of Pharmaceutics, Crescent School of Pharmacy, B.S. Abdur Rahman Crescent Institute of Science and Technology, GST Road, Vandalur, Chennai, Tamil Nadu, India
  • Mohamed Asrarullah M.H Department of Pharmaceutics, Crescent School of Pharmacy, B.S. Abdur Rahman Crescent Institute of Science and Technology, GST Road, Vandalur, Chennai, Tamil Nadu, India

Keywords:

Silver Nanoparticles, Antibacterial Activity, biosynthesis, topical gel

Abstract

Silver nanoparticles, or AgNPs, are among the several metallic NPs with a wide range of uses in the biotechnological and medicinal domains. AgNPs can be synthesised using chemical and physical means. Conversely, the usage of hazardous chemicals, higher energy limitations, and high operating costs are some of the disadvantages of physicochemical techniques. Physical operations are intricate processes that are unable to control nanoscale particle sizes. The two main disadvantages are that their manufacturing costs are considerable and they produce particles with unpredictable sizes. Chemically produced NPs have a high energy need, are not environmentally friendly, and are not cost-effective. This is the time to use biological methods that use less expensive sources as precursors of AgNPs. The goal of the current work is to develop a straightforward, quick, and affordable process for producing silver nanoparticles (AgNPs) from a herbal extract of coriander sativum Linn. Additionally, the gel was assessed using the agar well diffusion method in an in vitro antibacterial assay. When tested against Staphylococcus aureus, E. coli, and Pseudomonas aeruginosa, the generated AgNPs integrated nano gel demonstrated antibacterial inhibitory efficiency that was comparable to the commercial product. Based on the findings, it can be said that the formulation may be used to treat wounds.            

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Published

2024-10-20

How to Cite

Ubaidulla Uthumansha, Mohammad Samiyullah. S, & Mohamed Asrarullah M.H. (2024). Biosynthesis And Assessment Of Antibacterial Activity Of Silver Nanoparticles Utilizing Herbal Extract. IJPAR JOURNAL, 13(4), 495–499. Retrieved from https://ijpar.com/ijpar/article/view/807