Future ICPMS - Advanced Dilution System Impact on Analytical Errors

Future ICPMS - Advanced Dilution System Impact on Analytical Errors

Authors

  • Ravisankar.M Department of Pharmaceutical Analysis, Srinivasan College of Pharmaceutical Sciences, Trichy
  • S. Alexandar Department of Pharmaceutical Analysis, Vinayaka Mission’s College of Pharmacy, Salem, Tamil Nadu, India
  • R. Senthil Kumar Prof & Head, Department of Pharmaceutical Chemistry, Swamy Vivekanandha College of Pharmacy, Tiruchengode, Tamil Nadu, India
  • P. Nataraj Novitium Pharma LLC, New jersey, USA
  • G. Ashley Joanna Srinivasan College of Pharmaceutical Sciences, Trichy

Keywords:

ICPMS, Errors, Advanced dilution system

Abstract

Analytical techniques such as Inductively Coupled Plasma Mass Spectrometry (ICP-MS) can examine biological fluid components at trace levels. Although some labs still use out-dated techniques such as atomic absorption and emission, there has been a steady shift in favour of ICP-MS, particularly in the last ten years. One of the primary causes of the extremely high sensitivity of ICP-MS is the fact that most naturally occurring elements are at least 75% ionised at ordinary plasma conditions. Dilution errors are a frequent issue that arises in a variety of contexts, such as ordinary life, chemical analysis, and laboratory testing. It describes the erroneous assessment or measurement of a substance's concentration brought on by sample dilution. There are several reasons why this error can happen, including poor technique, limited equipment, or human error. Agilent Technologies created the auto dilution system (ADS-2) in the ICPMS to prevent manual dilution falls.

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Published

2025-09-04

How to Cite

Ravisankar.M, S. Alexandar, R. Senthil Kumar, P. Nataraj, & G. Ashley Joanna. (2025). Future ICPMS - Advanced Dilution System Impact on Analytical Errors. International Journal of Pharmacy and Analytical Research, 14(3), 602–606. Retrieved from https://ijpar.com/ijpar/article/view/952